Reactivity of 2-acylaminoacrylates with ketene diethyl acetal; [2 + 2] cycloadditions vs. tandem condensations.
نویسندگان
چکیده
The reactivity of 2-acylaminoacrylates with ketene diethyl acetal can be modulated by means of thermal conditions to yield cyclobutanes for the preparation of protected beta-hydroxycyclobutane-alpha-amino acids, or catalytic conditions that yield cyclohexanes by tandem condensations to obtain interesting building blocks that are alternatives to Danishefsky's diene.
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ورودعنوان ژورنال:
- Chemical communications
دوره 12 شماره
صفحات -
تاریخ انتشار 2003